How to get BEQVEZ
No matter where you are in your journey, we’re here to give you educational support, tools, and resources to help
Click an icon to learn about each step
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Here’s how to get started
STEP 1:
Discuss BEQVEZ with your doctor
We understand getting gene therapy is an important decision
As with any new treatment, it’s normal to have questions.
- The first step is to talk to your doctor to see if BEQVEZ is right for you
- Talking to your loved ones is also important
- Choosing BEQVEZ is a decision you don’t have to make alone
BEQVEZ may be an option if you:
- Are male and 18 years of age or older
- Have moderate to severe hemophilia B
Your doctor will tell you about lifestyle changes you may need to make before getting BEQVEZ, like:
- Limiting alcohol during the first year after the BEQVEZ infusion
- Not donating sperm and being abstinent or using a male condom for the first 6 months after your infusion
Ready to talk to your doctor about BEQVEZ?
Take a 2-minute survey to create your own personalized discussion guide that you can bring with you to your next appointment.
STEP 2:
Confirm your eligibility
To find out if BEQVEZ is right for you, you and your doctor will talk about considerations like potential lifestyle changes. You will also need lab testing and confirmation of your access and insurance coverage to see if you’re eligible for BEQVEZ.
Your doctor will check your eligibility with various tests to confirm if BEQVEZ may be a treatment option for you
These tests include, but are not limited to, checking:
- your liver health
- for factor IX (FIX) inhibitors
- to see if you have any neutralizing antibodies (NAbs) to BEQVEZ
You will get the results from your NAb test after about 7 to 10 days.
Your care team will talk to you about your results and whether BEQVEZ is right for you.
Pfizer GeneTogether™ is here to help answer your coverage and logistics questions throughout your BEQVEZ journey
After you and your doctor decide BEQVEZ is the right treatment choice for you, your care team will work with you to enroll you in Pfizer GeneTogether.
STEP 3:
Receive your one-time BEQVEZ infusion
On the day of your infusion, you should plan to spend all day at the gene therapy infusion center.
This includes preparation time for your infusion. You may need to fill out some paperwork.
The process before, during, and after the infusion may vary across centers.
STEP 4:
After-treatment experience and monitoring
It will be important to see your care team for post-infusion monitoring routinely after the infusion.
You will have blood tests to assess your liver health and FIX activity levels.
In the clinical trial for BEQVEZ, some participants had raised liver enzyme levels and/or a decrease in FIX activity levels. Depending on their levels, these participants were prescribed corticosteroids.
Your care team will also remind you about:
- Limiting alcohol during the first year after the BEQVEZ infusion
- Not donating sperm and being abstinent or using a male condom for the first 6 months after your infusion
Talk to your doctor about enrolling in a registry to assess the long-term efficacy and safety of treatments for hemophilia.
After the infusion, when do you need to have scheduled follow-ups?
Post-infusion follow-ups, which include blood draws, are done 1 or 2 times a week in the first 4 months after receiving BEQVEZ and lessen over time.
Your care team may suggest that you visit the same lab for all your tests. This may help minimize any potential variability in results.
You can also speak to your doctor and nurse who may be able to help guide you to resources and tools after your BEQVEZ infusion.
